“In a small, preliminary study, an experimental gene-editing treatment
dramatically lowered cholesterol levels, perhaps permanently, after just
one infusion, scientists reported on Monday. If confirmed in larger
studies, researchers hope the findings may lead to a one-and-done way to
prevent heart disease in large numbers of people. Most gene therapies
target rare diseases, but cardiovascular […]
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#^One-and-Done Heart Disease Prevention May Be Possible“In a small, preliminary study, an experimental gene-editing treatment dramatically lowered cholesterol levels, perhaps permanently, after just one infusion, scientists reported on Monday.
If confirmed in larger studies, researchers hope the findings may lead to a one-and-done way to prevent heart disease in large numbers of people. Most gene therapies target rare diseases, but cardiovascular disease kills nearly 800,000 Americans a year…
The
study, published in The New England Journal of Medicine, was an interim analysis of 35 patients in a trial that will involve as many as 85 participants. All have genetically high levels of LDL cholesterol — the bad kind — or heart disease.
In the 35 patients, a single infusion of the highest dose of the treatment reduced LDL cholesterol levels by as much as 62 percent. The change has been sustained in a subgroup whose members were treated 18 months ago.
It will be followed by a larger study of 200 patients.”
From
New York Times.
The post
One-and-Done Heart Disease Prevention May Be Possible appeared first on
Human Progress.
