CAR-T buňka je T lymfocyt, který je geneticky upraven(ano, CRISPR-Cas9) tak, aby napadal např. rakovinné buňky. Aby nenapadal tělo, resp. imunitní systém nelikvidoval CAR-T, musí se brát od pacienta, geneticky upravit, namnožit a pak vstříknout pacientovi. To je drahé jak prase.
Číňani vzali T lymfocyty od mladé zdravé ženy, geneticky upravili tak, aby byly neviditelné pro imunitní systém, pak geneticky upravili na hon zblblých B buněk, které vytvářejí autoprotilátky, a hle! Pacoši s těžkými autoimunními nemocemi jsou v remisi!
To je docela bomba... 💣
New Therapy Sends Autoimmune Diseases Into Remission
“One woman and two men with severe autoimmune conditions have gone into
remission after being treated with bioengineered and CRISPR-modified
immune cells. The three individuals from China are the first people with
autoimmune disorders to be treated with engineered immune cells created
from donor cells, rather than ones collected from their own bodies. This
advance […]
The post New Therapy Sends Autoimmune Diseases Into Remission appeared
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#^New Therapy Sends Autoimmune Diseases Into Remission“One woman and two men with severe autoimmune conditions have gone into remission after being treated with bioengineered and CRISPR-modified immune cells. The three individuals from China are the first people with autoimmune disorders to be treated with engineered immune cells created from donor cells, rather than ones collected from their own bodies. This advance is the first step towards mass production of such therapies.
One of the recipients, Mr Gong, a 57-year-old man from Shanghai, has systemic sclerosis, which affects connective tissue and can result in skin stiffening and organ damage. He says that three days after receiving the therapy, he felt his skin loosen and he could start moving his fingers and opening his mouth again. Two weeks later, he returned to his office job. ‘I feel very good,’ he says, more than a year after receiving the treatment.”
From
Nature.
The post
New Therapy Sends Autoimmune Diseases Into Remission appeared first on
Human Progress.
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CRISPRCAS9 #
CAR-T
